Tablets contain the following inactive ingredients: lactose, microcrystalline cellulose, Conseils Une crise de goutte peut être provoquée par un excès alimentaire mais aussi par un jeûne prolongé, une … Recommended dose is 80 mg once daily. Peak plasma concentration: ~1.6 mcg/mL (40-mg dose); 2.6 mcg/mL (80-mg dose) Peak plasma time: 1-1.5 hr. - Keep this leaflet. This usually reduces blood uric acid levels within two weeks, but the dose can be increased to 120 mg once a day if blood uric acid levels remain high (above 6 mg per decilitre) after two to four weeks. You may need to read it again. ADENURIC 80 mg film-coated tablets ADENURIC 120 mg film-coated tablets Febuxostat Read all of this leaflet carefully before you start taking this medicine because it contains important information for you. Adenuric 80 mg tablets are pale yellow to yellow, film-coated, rectangular shaped tablets, with a break line on one side and "80" engraved on the other side. Dosage and administration: Oral use with or without food. « La dose recommandée d’ADENURIC est de 80 mg une fois par jour, administrée par voie orale, pendant ou en dehors des repas. 4.1 Therapeutic Indications La dose peut être augmentée après quelques semaines de traitement en fonction du taux d'acide urique dans le sang. If serum uric acid is > 6 mg/ dl (357 µmol/l) after 2-4 weeks, 120 mg once daily may be considered. They are immediate release tablets containing 80 mg of febuxostat as the active substance. If serum uric acid levels remain > 0.36 mmol/L after 2–4 weeks, increase dose to 80 mg once daily. 4 Clinical Particulars. The dosage is based on your medical condition and response to treatment. The recommended dose of Adenuric is 80 mg once a day. For the treatment of long-term hyperuricaemia, the recommended dose of Adenuric is 80 mg once a day. There may be an initial increase in gout flares Consider concurrent prophylaxis for at least 6 months with low-dose colchicine or an NSAID. No data is available for febuxostat 120 mg. They are immediate-release tablets containing 80 mg of febuxostat as the active substance. - If you have … The recommended starting dose is 40 mg once daily (achieved by halving one 80 mg tablet). Drug Details; Registration No: 13-313-16: Trade Name: ADENURIC 80 mg film-coated tablet: GenericName: FEBUXOSTAT: Strength Value: 80 mg: Dosage Form: TABLET, FILM COATED ADENURIC 80 mg tablets are pale yellow to yellow, film-coated, rectangular shaped tablets, with a break line on one side and “80” engraved on the other side. Co-administration of febuxostat 80 mg and theophylline 400mg single dose in healthy subjects showed absence of any pharmacokinetic interaction (see section 4.5). This usually reduces blood uric acid levels within two weeks, but the dose can be increased to 120 mg once a day if blood uric acid levels remain high (above 6 mg per decilitre) after two to four weeks. Adulte: 1 comprimé à 80 mg par jour. Protein bound: 99.2%. Following multiple 80 mg qDay doses with a high fat meal, peak plasma concentration decreased by 49% and AUC decreased by 18%. Older people: No dose adjustment required. Si l’uricémie est > 60 mg/l (360 µmol/l) après deux à quatre semaines de traitement, l’administration d’ADENURIC 120 mg une fois par jour peut être envisagée. Distribution. Vd: 50 L. Metabolism Renal impairment: No dosage adjustment necessary in patients with mild or moderate renal impairment. Les informations sur le médicament ADENURIC 80 mg cp pellic sur VIDAL : Formes et présentations, Composition, Indications, Posologie et mode d'administration, Febuxostat 80 mg can be used in patients concomitantly treated with theophylline without risk of increasing theophylline plasma levels.
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