you are allergic to glucagon or lactose or any of the ingredients in Glucagon. Hypoglycemia can be unpredictable, but your solution is not. Be … The primary effect of Glucagon is to promote the release of stored glucose in the liver and stimulate the release of insulin from the pancreas to promote uptake of glucose into the cells. The usual adult dose is 1 mg. For children weighing less than 44 lbs (20 kg), give ½ adult dose (0.5 mg). you have a tumor in your pancreas called an insulinoma. GLUCAGON IS A KEY REGULATOR OF GLUCOSE HOMEOSTASIS IN VIVO. Following a glucagon injection, an unconscious person with hypoglycemia (low blood sugar) will usually wake within 15 minutes. If the patient does not improve within 15 minutes, you may need to mix a new dose and give a second injection. Glucagon medication triggers the release of glucose from the liver to increase blood sugar levels, just as the natural hormone is supposed to do. Ask your healthcare provider for multiple kits — one for at home, one for school or the office. Last updated on Sep 23, 2020. Insulin may then be released to balance the system … Glucagon plays a key role in glucose metabolism in vivo. Teach your family, friends, and coworkers how to use the Glucagon Emergency Kit. Glucagon … Be sure you know how to give a glucagon injection before you need to use it. A child's dose may also be based on how much the child weighs. Call your doctor for medical advice about side effects. Available for Android and iOS devices. Avoid drinking alcohol. Following a glucagon injection, an unconscious person with hypoglycemia (low blood sugar) will usually wake within 15 minutes. Ask your doctor about any risk. Patients who must take the hormone for low blood pressure while using anticoagulants should be monitored by a health care professional. After administration, call for emergency medical attention. Do not prepare Glucagon for Injection until you are ready to use it. Use glucagon exactly as prescribed by your doctor. Read and understand the Instructions for Use in the package insert before an episode occurs. Glucagon is a hormone that increases blood sugar levels. Medically reviewed by Philip Thornton, DipPharm. This Important Safety Information does not include all the information needed to use Glucagon for Injection safely and effectively. Glucagon is a hormone produced by alpha cells in the islets of Langerhans of the pancreas. It is does occur if the blood glucose level is low and so GLP-1 medications do not tend to cause hypoglycaemia or low blood sugar levels. ACTIVATION IS NOT REQUIRED. Glucagon can actually raise your blood sugar by converting glycerol in your fat cells into glucose for fuel. Store the auto-injector or prefilled syringe in the foil pouch and use the medicine right away after opening. The Glucagon Emergency Kit from Fresenius Kabi is a cost effective alternative to emergency solutions you have trusted for years. If you are a caregiver, get emergency medical help after giving a glucagon injection. Avoid these tasks or actions until you feel fully alert. Overdose symptoms may include nausea, vomiting, diarrhea, rapid pulse, or high blood pressure (severe headache, blurred vision, pounding in your neck or ears). You will be shown how to use the emergency injections for severe hypoglycemia. The full prescribing information is also available at www.fresenius-kabi.com/us. The pancreas secretes insulin and glucagon. The most common cause of ketoacidosis is diabetic ketoacidosis … you have not recently eaten on a regular basis; or. are breastfeeding or plan to breastfeed. To do this, hold the vial and syringe so that the vial remains on top and the tip of the syringe is towards the bottom of the vial (see Figure 5). Avoid driving and doing other tasks or actions that call for you to be alert until you have eaten sugar or a product that has sugar in it like a regular soft drink or fruit juice. Glucagon should be used to treat hypoglycemia only if the person cannot eat, passes out, or is having a seizure. Intravenous or powdered glucagon is given to the individual to help restore sugar levels in the body and prevent further hypoglycemia. In an emergency situation it may not be possible to tell your caregivers if you are pregnant or breast-feeding. It is not known if Glucagon passes into your breast milk. Low blood sugar can happen with this medicine (glucagon auto-injectors and prefilled syringes) in people who have certain types of pancreas tumors (glucagonoma, insulinoma). The correct dose for a child is lower than an adult dose. Call your doctor promptly if symptoms do not improve after using glucagon. If the person does not awaken within 15 minutes after an injection, give one more dose of glucagon. To be prepared, we recommend that you: Fresenius Kabi’s Glucagon Emergency Kit is a cost-effective alternative to emergency solutions you have trusted for years. Do not prepare Glucagon for Injection until you are ready to use it. For children, withdraw ½ of the solution from the vial (0.5 mg mark on syringe). Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. In the event of a severe hypoglycemic episode, you will be unable to treat yourself. Store glucagon and any diluent at room temperature, away from moisture, heat, and light. Glucagon may affect the way other medicines work, and other medicines may affect how Glucagon works. Glucagon is also used to stop stomach movement during radiologic (x-ray) examinations undertaken to diagnose certain disorders of the stomach or intestines. Throw away any mixed medicine you have not used right away. Prepare an injection only when you are ready to give it. For patients with diabetes, a hypoglycemic episode can occur anywhere, anytime. Eat sugar or a sugar sweetened product such as a regular soft drink or fruit juice as soon as you are able to swallow. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. BAQSIMI is a prescription medicine used to treat very low blood sugar (severe hypoglycemia) in people with diabetes ages 4 years and above. Glucagon should not be used unless the solution is clear and of a water-like consistency. Are glucagon and glycogen the same thing? When they do their jobs correctly, they can balance your … Both hormones work in balance to play a vital role in regulating blood sugar levels. Ready to Go – Whether you are at home, school, work, or on-the-go, the kit goes with you. Glucagon works on cells in the liver, causing the release of glucose. Do not use this medicine after the expiration date on the label has passed. How does the release of glucagon affect blood glucose levels. It can lower your blood sugar. Follow your doctor's dosing instructions very carefully. have low blood sugar that does not go away (chronic hypoglycemia). Glucagon is a fat-burning and unlocking hormone. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Since glucagon is used as needed, it does not have a daily dosing schedule. You may report side effects to FDA at www.fda.gov/medwatch or call 1-800-FDA-1088. Glucagon is a prescription medicine used to treat very low blood sugar (hypoglycemia). Having low blood sugar for too long can cause seizure, coma, or death. Ask your healthcare provider for multiple kits — one for at home, one for school or the office. Insulin vs Glucagon - What do they have in common? Keep a list of them to show your doctor and pharmacist when you get a new medicine. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use glucagon only for the indication prescribed. you have a tumor in the gland on top of your kidneys (adrenal gland) called a pheochromocytoma. Do not use if the medicine has changed colors or has particles in it. Ltd –: Global Glucagon Market: Products, Materials, Applications, Growth Rates and Shares, and Forecast: 2020 – 2029 is the title of one of the recently produced reports by research team at Market.US.The global glucagon … Many other medicines can affect your blood sugar, and some medicines can increase or decrease the effects of medicines used to treat diabetes. Call your doctor after each time you use a glucagon injection. Glucagon Trade Names: Glucagen, Glucagon Class: Pancreatic hormone, anti-hypoglycemic agent Pharmacology: Onset: within 1 min Duration: 60-90 min Results in blood glucose elevation by increasing the breakdown of glycogen to glucose and stimulating glucose synthesis. Glucagon is a prescription medicine used to treat very low blood sugar (hypoglycemia). Glucagon is available as an auto-injector, prefilled syringe, or injection vial. Do not use expired glucagon. Ketoacidosis is a metabolic state caused by uncontrolled production of ketone bodies that cause a metabolic acidosis.While ketosis refers to any elevation of blood ketones, ketoacidosis is a specific pathologic condition that results in changes in blood pH and requires medical attention. Types of glucagon Glucagon is available as an auto-injector, prefilled syringe, or injection vial. This injection is administered under the skin to quickly treat patients with diabetes who experience unexpected episodes of severe hypoglycemia. Eye Catching – The bright orange case makes it easy for you, or your caregiver, to find it and act quickly. are pregnant or plan to become pregnant. We comply with the HONcode standard for trustworthy health information -. Version: 5.03. diazoxide, mannitol, arginine, Lexiscan, inulin, Baqsimi, Thyrogen, GlucaGen, Gvoke. Glucagon triggers the liver to release stored sugar, which raises blood sugar in the event of a severe hypoglycemic episode. Fresenius Kabi’s Glucagon Emergency Kit is a cost-effective alternative to currently marketed branded kit products. Having low blood sugar for too long can cause seizure, coma, or death. Tell your doctor each time you use Glucagon. If signs of low blood sugar happen after using this glucagon, get medical help right away. Reduces the amount of glucose that your liver is producing. Causes positive inotropic effect on the heart and decreases renal vascular resistance Indications: Hypoglycemia, Calcium … Call your pharmacist for new medicine. If the person does not respond after 15 minutes, another dose may be given, if available. Ask your doctor before changing your dose or medication schedule. For children, withdraw ½ of the solution from the vial (0.5 mg mark on syringe). All Rights Reserved.Fresenius Kabi USA Terms of Use Privacy Policy. Glucagon may cause serious side effects, including: The most common side effects of Glucagon include: Tell your doctor if you have any side effect that bothers you or that does not go away. Hypoglycemia should be treated as quickly as possible. Make sure any doctor caring for your pregnancy or your baby knows you have received this medicine. Glucagon should not be used unless the solution is clear and of a water-like consistency. Glucagon does interact with certain medications, specifically anticoagulants like Warfarin. If the level of one hormone is higher or lower than the ideal … Indication and UsageGlucagon is a prescription medicine used to treat very low blood sugar (severe hypoglycemia) in people with diabetes. Show them where you keep it. This is a factor boosting growth of the global glucagon … Brand Name: GlucaGen, GlucaGen HypoKit, Glucagon Emergency Kit for Low Blood Sugar, Gvoke HypoPen, Gvoke PFS. The big thing to remember about insulin and glucagon is that these two hormones work together to regulate your blood glucose levels. The safety of glucagon during pregnancy and while nursing is unclear, but the risk to the unborn fetus is considered low. Glucagon signals the … Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Use Glucagon exactly as your doctor tells you to. After the injection, you should eat a fast-acting source of sugar (fruit juice, glucose gel, hard candy, raisins, or non-diet soda) and then eat a snack or small meal such as cheese and crackers or a meat sandwich. Before using Glucagon, tell your doctor about all of your medical conditions, including if you: Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. ©2020 Fresenius Kabi USA, LLC. Glucagon should not be used unless the solution is clear and of a water-like consistency. Make sure that you and your family know how to use Glucagon the right way before you need it. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. It is not known if Glucagon will harm your unborn baby. It is not known if … Administration of exogenous glucagon increases glucose levels in fasted or fed animals (63, 96), and similar observations were made in humans (29, 42, 57).Consistent with its role as a counterregulatory hormone of insulin, glucagon … Do not prepare Glucagon for Injection until you are ready to use it. Draw up the glucagon into the syringe. Call your doctor at once if you have any of the following skin changes on your face, legs, groin, or genital area: Common glucagon side effects may include: This is not a complete list of side effects and others may occur. Read the detailed Instructions for Use that come with Glucagon. Call your doctor for medical advice about side effects. Be sure you know how to give a glucagon injection before you need to use it. If sugar levels in the blood rise above normal, the pancreas stops releasing glucagon. To learn more about Glucagon for Injection, talk to your doctor or pharmacist. You should not use this medicine if you are allergic to glucagon or lactose, or if you have: a tumor of the adrenal gland (pheochromocytoma). Two cases of severe beta-blocker overdose are presented that were treated successfully with glucagon therapy. Get emergency medical help if you have signs of an allergic reaction to glucagon: hives; difficulty breathing; fast or slow heartbeat; swelling of your face, lips, tongue, or throat. Data sources include IBM Watson Micromedex (updated 3 Mar 2021), Cerner Multum™ (updated 1 Mar 2021), ASHP (updated 3 Mar 2021) and others. The FDA-approved Glucagon Emergency Kit contains: 1 vial of Glucagon for Injection (1 mg) 1 disposable syringe with sterile water (1 mL) for reconstitution, A Cost-Effective Alternative from an Experienced, Reliable Supplier. Glucagon and insulin, another kind of hormone, should work as a team to keep your blood sugar in balance. Hypoglycemia should be treated as quickly as possible. The usual adult dose is 1 mg. For children weighing less than 44 lbs (20 kg), give ½ adult dose (0.5 mg). Once the glucagon has been given, immediately contact a doctor and get emergency medical treatment. Fresenius Kabi’s Glucagon … Glucagon also signals the fat cells to release free fatty acids (a process called lipolysis). - Glucagon should not be considered as first-line choice for hypoglycemia - May cause vomiting and hyperglycemia - IV glucose will need to be administered if the pt does not respond to a second dose of glucagon - Do not use the provided dilute the to mix continuous infusions If it becomes necessary to inject glucagon, a family member or friend should know the following: After the injection, turn the patient on his or her left side. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. When using injections by yourself, be sure you understand how to properly mix and store the medicine. Automated insulin delivery systems are automated (or semi-automated) systems designed to assist people with diabetes, primarily type 1, by automatically adjusting insulin delivery to help them control … Very low blood sugar can lead to seizures, confusion, passing out, and sometimes death. Ask your doctor or pharmacist if you don't understand all instructions. Simple and Easy – From the package to the syringe, the kit is simple and easy to use. Make sure that you and a member of your family or a friend understand exactly when and how to use this medicine before it is needed. Glucagon may cause some patients to vomit and this position will reduce the possibility of choking. You may report side effects to FDA at 1-800-FDA-1088. Not all possible interactions are listed here. Glucagon is also used to stop stomach movement during radiologic (x-ray) examinations undertaken to diagnose certain disorders of the stomach or intestines. You should not use glucagon injection if you are allergic to glucagon or lactose, or if you have a tumor of the pancreas (insulinoma) or adrenal gland (pheochromocytoma). Glucagon is injected under the skin, into a muscle, or into a vein. Glucagon injection is an emergency medicine and must be used only as directed by your doctor. You will need help from others. You may need to mix glucagon with a liquid (diluent) before using it. The usual adult dose is 1 mg. For children … This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Generic Name: glucagon (injection) (GLOO ka gon) Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Act quickly. Pull the plunger of the syringe back to draw the Glucagon into the syringe. Pune, India, March 08 2021 (Wiredrelease) Prudour Pvt. Glucagon is a prescription medicine used to treat very low blood sugar (hypoglycemia). Know the medicines you take. Unconscious patients usually return to consciousness within 5 to 20 minutes of receiving glucagon… Please see the full prescribing information for Glucagon for Injection and Patient Information. Do not refrigerate or freeze. INSTRUCTIONS FOR USE. To keep from having severe hypoglycemia, follow your diet, medication, and exercise routines very closely. The effects of glucagon in reversing the cardiovascular depression of profound beta-blockade, including its mechanism of action, onset and duration of action, dosage and administration, cost and availability, and side effects are reviewed. Do not use expired glucagon. Having very low blood sugar for a period of time may be harmful. Some drugs can also cause you to have fewer symptoms of hypoglycemia, making it harder to tell when your blood sugar is low. If the person does not awaken within 15 minutes after an injection, give one more dose of glucagon. Once the glucagon has been given, immediately contact a doctor and get emergency medical treatment. Read and carefully follow any Instructions for Use provided with your medicine. Check the expiration date. Typically, the liver produces glucose, and it does … Tell your doctor about all medicines you start or stop using. The Glucagon Emergency Kit contains glucagon for injection. Glucagon is also used to stop stomach movement during radiologic (x-ray) examinations undertaken to diagnose certain disorders of the stomach or intestines. At home, school or work, the Glucagon Emergency Kit is convenient and simple to use. It also slows involuntary muscle movements of the stomach and intestines that aid in digestion. After administration, call for emergency medical attention. These are not all the possible side effects of Glucagon. Your doctor may need to change the dose of your diabetes medicines. Copyright 1996-2021 Cerner Multum, Inc. The glucagon powder must first be dissolved using the diluting fluid provided. Glucagon should be given and the patient's doctor should be called at once. have not had food or water for a long time (prolonged fasting or starvation). A co-pay assistance program is available for eligible patients. It may not be safe to breastfeed while using this medicine. Warnings *Terms & Conditions. Glucagon is not expected to harm an unborn baby, but quickly treating hypoglycemia would outweigh any risks posed by using glucagon. It is also known as glucagon nasal powder. Use this medication immediately after it has been mixed. Do not give this medicine to a child without medical advice. Select one or more newsletters to continue. Glucagon should be used to treat hypoglycemia only if the person is unable to eat, or is unconscious or having a seizure. The FDA-approved Glucagon Emergency Kit, provides flexibility and choice. The cells in your pancreas that make glucagon are similar to cells that make insulin .
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