Our Lantus (insulin glargine [rdna origin]) Injection Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Low blood sugar (hypoglycemia) is a side effect of all forms of insulin. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. You may report side effects to FDA at 1-800-FDA-1088. Last updated on Nov 16, 2020. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Below, we describe certain interactions and the drugs … Although not all of these side effects may occur, if they do occur they may need medical attention. "Product Information. Applies to insulin isophane: subcutaneous suspension, Frequency not reported: Sodium retention and edema[Ref], Insulin may cause sodium retention and edema, especially with intensified insulin therapy. Some of the dosage forms listed on this page may not apply to the brand name NPH Insulin.. For the Consumer O 0. help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. O 0, 3. Some people with type 2 diabetes can benefit from using both medication and insulin. [Ref], Uncommon (0.1% to 1%): Lipodystrophy[Ref], Long-term use of insulin can cause lipodystrophy at the site of repeated insulin injections. [Ref], Common (1% to 10%): Injection site hypertrophy, Frequency not reported: Injection site reactions[Ref], Injection site reactions including pain, redness, hives, inflammation, bruising, swelling, and itching have occurred. Localized reactions have been reported with metacresol, which is an excipient in many insulin products. A person with diabetes who has hyperglycemia frequently or for long periods of time may suffer damage to the blood vessels, nerves, and organs. If you have questions about side effects, call your doctor. Changing to insulin can actually be a lot better. Common side effects of insulin include hypoglycemia, headache, weight gain, rash, itching, flu-like symptoms, lipoatrophy, and reaction at the site of injection. [Ref], Transitory, reversible ophthalmologic refraction disorder and worsening of diabetic retinopathy has been reported with insulin initiation and glucose control intensification. True allergy to insulin has been rare, and sensitization was usually associated with specific animal proteins in bovine and less pure forms of porcine insulins. For people with diabetes, either the pancreas does not make enough insulin to meet the body's requirements, or the body cannot properly use the insulin that is made. SLIDESHOW … advice about side effects. Hypoglycemia is the most common adverse reaction of all insulin therapies. Other factors such as changes in food intake (timing of meals, amount or type of food) and concomitant medications will also affect the risk of hypoglycemia. What are the side effects? 2. Although not all of these side effects may occur, if they do occur they may need medical attention. Last updated on April 26, 2020. Drugs and Supplements Insulin Human Regular (Injection Route) Description and Brand Names. 4. Insulin increases the intracellular transport of phosphate, which often results in hypophosphatemia during treatment of DKA. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. They usually occurred within the first two weeks of therapy and then disappear. The main side effects of insulin have to do with taking too little or too much of the drug. Hypersensitivity reactions have included both local and systemic reactions. Check with your doctor immediately if any of the following side effects occur while taking insulin regular: Some side effects of insulin regular may occur that usually do not need medical attention. Novo Nordisk Pharmaceuticals Inc, Princeton, NJ. The right dosage will provide benefit without harm. Generalized allergy to insulin may present as a whole body rash, dyspnea, wheezing, hypotension, tachycardia, or diaphoresis. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. No diabetes medication is free from side effects, but these are some of the worst offenders. It puts people at risk for: Some side effects may not be reported. There are various side effects that occur from insulin. Some side effects of liraglutide may occur that usually do not need medical attention. Anaphylaxis has been reported. Call your doctor for medical Novo Nordisk Pharmaceuticals Inc, Princeton, NJ. 4. [Ref], Uncommon (0.1% to 1%): Local reactions such as redness, swelling, or itching at the injection site, Very rare (less than 0.01%): Anaphylactic reactions[Ref], Hypersensitivity side effects have included both local and systemic reactions. "Product Information. A slow erosion of health is the silent, insidious danger of not taking medications as necessary for type 1 or type 2 diabetes. Side Effects. [Ref], Frequency not reported: Formation of anti-insulin antibodies[Ref], Rare (less than 0.1%): Insulin resistance, Frequency not reported: Hypokalemia, hyperglycemia, diabetic ketoacidosis, hyperosmolar hyperglycemic non-ketotic syndrome, hypomagnesemia, hypophosphatemia[Ref]. Humulin R (insulin regular)." Available for Android and iOS devices. Cerner Multum, Inc. "Australian Product Information." Hypokalemia and hypomagnesemia has been reported, particularly in patients treated for diabetic ketoacidosis (DKA). These usually resolve in a few days to a few weeks; rotation of the injection site reduces the risk of these reactions developing. Unfortunately, insulin can cause weight gain, interactions with other medications, headaches, and nausea. Keep in mind that most of the side effects of insulin are actually the result of inaccurate doses and improper injection practices. It only works for 2 to 4 hours. Commonly reported side effects of insulin regular include: hypoglycemia. The former can result in high blood sugar, or hyperglycemia. Over the long-term, improved glycemic control decreases the risk for diabetic neuropathy. Along with its needed effects, a medicine may cause some unwanted effects. Available for Android and iOS devices. Most minor reactions to insulin at the injection site resolve in a few days to a few weeks. Side effects include nausea, hunger, headache, blurred vision, irritability, heart palpitations, and tremors. Combination use with thiazolidinediones has resulted in fluid retention which has led to or exacerbated heart failure. Long-Term Dangers. Cerner Multum, Inc. "UK Summary of Product Characteristics." US Brand Name. Children may be more sensitive to the side effects of this drug, especially low blood sugar. Other side effects include: weight gain. [Ref], Increases in titers of anti-insulin antibodies that react with human insulin have been observed; some data indicates the increase is transient. Low blood sugar O 0. It is also used along with glucose to treat high blood potassium levels. You may report them to the FDA. Some of the dosage forms listed on this page may not apply to the brand name NPH Insulin. This is not a complete list of side effects and others may occur. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Over the long-term, improved glycemic control decreases the risk for neuropathy. Tell your The drug interactions can vary — some cause the insulin to work less well, while others cause side effects to become more severe. Hypokalemia, which is due to a shift in potassium from the extracellular to the intracellular space, occurs with all insulins. Like all medications, you need to take insulin in the right amounts. [Ref], Frequency not reported: Transitory, reversible ophthalmologic refraction disorder, worsening diabetic neuropathy[Ref], Uncommon (0.1% to 1%): Lipodystrophy[Ref], Long-term use of insulin can cause lipodystrophy at the site of repeated insulin injections. [Ref], Frequency not reported: Acute painful peripheral neuropathy[Ref], Weight gain can occur with insulin use; it is believed to be due to the anabolic effects of insulin and the decrease in glucosuria.[Ref]. It may cause you to hang on to fluids in your body, which can lead to swelling. O 0, 3. Other Possible Insulin Side Effects. However, some patients experience an interference with … [Ref], The most common adverse reactions reported with this insulin include hypoglycemia, allergic reactions, injection site reactions, lipodystrophy, weight gain, and edema. Call your doctor or get medical [Ref], Uncommon (0.1% to 1%): Local reactions such as redness, swelling, or itching at the injection site, Very rare (less than 0.01%): Anaphylactic reactions, Postmarketing reports: Severe, life-threatening, generalized allergy, including anaphylaxis[Ref]. Also, each type of insulin has its own profile of possible side effects. Rapid-acting insulin starts to work almost immediately after you inject it. Local reactions have presented as erythema, local edema, and pruritus at the injection site. [Ref], Frequency not reported: Formation of anti-insulin antibodies[Ref], Frequency not reported: Sodium retention and edema[Ref], Insulin may cause sodium retention and edema, especially with intensified insulin therapy. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site, redistribution or accumulation of body fat. Other factors such as changes in food intake (timing of meals, amount or type of food) and concomitant medications will also affect the risk of hypoglycemia. Over the long-term, improved glycemic control decreases the risk for diabetic neuropathy. "Product Information. Medically reviewed by Drugs.com. Applies to insulin regular: injection solution. Note: This document contains side effect information about insulin isophane. Insulin human regular is a short-acting type of insulin. 1. Hypoglycemia is the most common adverse reaction of all insulin therapies. Weight gain has been reported and has been attributed to the anabolic effects of insulin and the decrease in glucosuria. We comply with the HONcode standard for trustworthy health information -. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products.
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